Randle H W
Department of Dermatology, Mayo Clinic Jacksonville, FL 32224, USA.
Dermatol Surg. 1996 Mar;22(3):255-61. doi: 10.1111/j.1524-4725.1996.tb00316.x.
Some cutaneous basal cell carcinomas have a significant potential to recur, disfigure, and metastasize.
The identification and selection of treatment of these high risk carcinomas is based on a review of studies of recurrence, giant size, metastasis, and mortality.
Basal cell carcinomas with any of the following: long duration, location in the mid face or ear, larger than 2 cm, with aggressive histologic subtype, previous treatment, neglected, or a history of radiation exposure, should be considered "high risk."
For basal cell carcinomas with this high risk profile, complete excision by margin control or total destruction should be considered.
一些皮肤基底细胞癌具有显著的复发、毁容和转移潜力。
对这些高危癌的识别与治疗选择基于对复发、巨大尺寸、转移和死亡率研究的综述。
具有以下任何一种情况的基底细胞癌：病程长、位于面中部或耳部、大于2厘米、具有侵袭性组织学亚型、既往接受过治疗、被忽视或有放疗史，应被视为“高危”。
对于具有这种高危特征的基底细胞癌，应考虑通过切缘控制进行完整切除或完全破坏。
