Box J C, Watne A L, Lucas G W
Department of Surgery, Baptist Medical Center, Atlanta, Georgia, USA.
Am Surg. 1996 Apr;62(4):280-6.
We have undertaken a review of the small bowel carcinoids treated at Georgia Baptist Medical Center during the last 27 years in order to evaluate the clinical behavior, diagnostic approaches, treatment options, and prognosis of these neoplasms. A retrospective analysis of the tumor registry at Georgia Baptist Medical Center was undertaken. A total of 148 cases of carcinoid tumors were identified. Of these, 34 were located in the small bowel. Twenty-eight of these cases were diagnosed at our institution. The others were referred for oncology care. The patient records were reviewed for sex, race, age at presentation, location, 5-HIAA status, coexistent neoplasms, multifocality, size, metastatic status, clinical presentation, diagnostic intervention, extension, adjuvant therapy, treatment intervention, and survival. A review of the available literature was undertaken to analyze the historical results in the aforementioned categories. In retrospect, many of these tumors had been clinically active for some time. The authors outline a more aggressive workup in order to avoid acute, in extremis, and late stage presentation. We present an analysis of traditional views on survival and prognosis as related to the size and spread of small bowel carcinoid. We expect that this information will assist in the development of definitive treatment, effective adjuvant therapy, and symptomatic relief for this often frustrating neoplasm.
我们对佐治亚浸信会医疗中心在过去27年中治疗的小肠类癌进行了回顾，以评估这些肿瘤的临床行为、诊断方法、治疗选择和预后。我们对佐治亚浸信会医疗中心的肿瘤登记处进行了回顾性分析。共识别出148例类癌肿瘤病例。其中，34例位于小肠。这些病例中有28例在我们机构被诊断出来。其他病例被转诊接受肿瘤治疗。我们查阅了患者记录，以了解性别、种族、就诊时年龄、位置、5-羟吲哚乙酸（5-HIAA）水平、并存肿瘤、多灶性、大小、转移状态、临床表现、诊断干预、肿瘤扩展、辅助治疗、治疗干预和生存情况。我们还查阅了现有文献，以分析上述类别中的历史结果。回顾过去，许多这些肿瘤在临床上已经活跃了一段时间。作者概述了一种更积极的检查方法，以避免急性、濒死期和晚期表现。我们对与小肠类癌大小和扩散相关的生存和预后的传统观点进行了分析。我们期望这些信息将有助于为这种常常令人沮丧的肿瘤制定明确的治疗方案、有效的辅助治疗方法并缓解症状。
