• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[Mechanisms of regulation and the biological role of carboxypeptidase H--a neuropeptide-processing enzyme].

作者信息

Vernigora A N, Gengin M T

出版信息

Biokhimiia. 1995 Dec;60(12):1953-63.

PMID:8600990
Abstract

The review summarizes contemporary views on the biological role, levels and mechanisms of regulation of carboxypeptidase H--the exopeptidase of secretory vesicles removing arginine and lysine residues from C-termini of peptides. It is concluded that although carboxypeptidase participates at the terminal stages of biological active peptide generation, it does not determine the levels of active neuropeptides in the organism.

摘要

相似文献

1
[Mechanisms of regulation and the biological role of carboxypeptidase H--a neuropeptide-processing enzyme].
Biokhimiia. 1995 Dec;60(12):1953-63.
2
Identification of incompletely processed potential carboxypeptidase E substrates from CpEfat/CpEfat mice.从CpEfat/CpEfat小鼠中鉴定未完全加工的潜在羧肽酶E底物。
Proteomics. 2001 Jan;1(1):79-92. doi: 10.1002/1615-9861(200101)1:1<79::AID-PROT79>3.0.CO;2-8.
3
Purification and characterization of the Manduca sexta neuropeptide processing enzyme carboxypeptidase E.烟草天蛾神经肽加工酶羧肽酶E的纯化与特性分析
Arch Insect Biochem Physiol. 1994;27(3):193-203. doi: 10.1002/arch.940270305.
4
Altered expression of the neuropeptide-processing enzyme carboxypeptidase E in the rat brain after global ischemia.
J Cereb Blood Flow Metab. 2001 Dec;21(12):1422-9. doi: 10.1097/00004647-200112000-00006.
5
Developmental changes in opioid peptides and their receptors in Cpe(fat)/Cpe(fat) mice lacking peptide processing enzyme carboxypeptidase E.缺乏肽加工酶羧肽酶E的Cpe(fat)/Cpe(fat)小鼠中阿片肽及其受体的发育变化。
J Pharmacol Exp Ther. 2002 Dec;303(3):1317-24. doi: 10.1124/jpet.102.037663.
6
Carboxypeptidase D is a potential candidate to carry out redundant processing functions of carboxypeptidase E based on comparative distribution studies in the rat central nervous system.基于在大鼠中枢神经系统中的比较分布研究,羧肽酶D是执行羧肽酶E冗余加工功能的潜在候选者。
Neuroscience. 1999;89(4):1301-17. doi: 10.1016/s0306-4522(98)00381-9.
7
Carboxypeptidase e: a surprise player in protein sorting.羧肽酶e:蛋白质分选过程中的意外参与者。
Nat Biotechnol. 1997 Feb;15(2):128-9. doi: 10.1038/nbt0297-128.
8
Processing of prodynorphin in BRL-3A cells, a rat liver-derived cell line: implications for the specificity of neuropeptide-processing enzymes.
Mol Cell Endocrinol. 1993 Jul;94(1):37-45. doi: 10.1016/0303-7207(93)90049-p.
9
[Effect of captopril and reserpine on the activity of certain neuropeptide metabolism enzymes].[卡托普利和利血平对某些神经肽代谢酶活性的影响]
Vopr Med Khim. 1995 Sep-Oct;41(5):37-9.
10
Relative quantitation of peptides in wild-type and Cpe(fat/fat) mouse pituitary using stable isotopic tags and mass spectrometry.使用稳定同位素标记和质谱法对野生型和Cpe(fat/fat)小鼠垂体中的肽进行相对定量。
J Mass Spectrom. 2005 Feb;40(2):227-37. doi: 10.1002/jms.742.