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胎儿血样中pH值的可靠性——第二阶段研究

The reliability of pH-values in fetal blood samples - A study of the second stage.

作者信息

Boenisch H, Saling E

出版信息

J Perinat Med. 1976;4(1):45-50.

PMID:8601
Abstract

In 119 cases fetal blood analysis (FBA) was done in the last 15 minutes before birth together with blood sampling from the umbilical artery (UA) immediately after delivery before the first breath. Using the measured pH-values we investigated the relationship between these variables, in particular the degree of influence of considerable caput succedaneum on pH-values in peripheral blood. Our investigation was performed during the time just before delivery, when the disturbance of blood circulation in the presenting fetal part whuld have the highest influence on pH-values measured from peripheral blood samples. We kept in mind especially the critiques of FBA by WULF et al. [21] and ASSALI [2]. As other authors have concluded, we found a high degree of correlation between the pH evaluated by FBA and that determined in the umbilical artery blood. The coefficient of correlation was: pHact r=0.82 pHqu40 r=0.78. The relationship between the corresponding pHvalues in peripheral (FBA) and arterial (UA) blood is given in Fig. 1 a and Fig. 1 b. The correlation of quadrants showed for the actual pH as well for the pHqu40 p less than 0.01. As derived form this, a high degree of correlation between the pH-values can be seen. The mean pH-values were: (see article) 42 of the children had a severe or moderate caput succedaneum. Fig. 2a and 2b show the relationship between central and peripheral pH-values in these cases. Again a good correlation between the pH-values was observed as in the whole collective. The coefficient of correlation was: pHact r=0.78 pHqu40 r=0.79. Caput succedaneum seems to have only minimal influence on the pH of blood obtained from the presenting fetal part. These results lead us to conclude that blood sampling from the presenting fetal part in the second stage provides almost indentical pH-values as in the central fetal blood.

摘要

在119例中,在出生前最后15分钟进行了胎儿血液分析(FBA),并在分娩后第一声啼哭前立即从脐动脉(UA)采血。利用测得的pH值,我们研究了这些变量之间的关系,特别是显著的头皮水肿对末梢血pH值的影响程度。我们的研究是在即将分娩时进行的,此时胎儿先露部血液循环的紊乱对从末梢血样本测得的pH值影响最大。我们特别牢记了WULF等人[21]和ASSALI[2]对FBA的批评。正如其他作者所总结的,我们发现通过FBA评估的pH值与脐动脉血中测定的pH值之间存在高度相关性。相关系数为:实际pH值r = 0.82,pHqu40 r = 0.78。末梢血(FBA)和动脉血(UA)中相应pH值之间的关系见图1a和图1b。象限相关性显示,实际pH值和pHqu40的p均小于0.01。由此可见,pH值之间存在高度相关性。平均pH值为:(见文章)42名儿童有严重或中度头皮水肿。图2a和2b显示了这些病例中中心和末梢pH值之间的关系。与整个群体一样,再次观察到pH值之间有良好的相关性。相关系数为:实际pH值r = 0.78,pHqu40 r = 0.79。头皮水肿似乎对从胎儿先露部采集的血液pH值影响极小。这些结果使我们得出结论,第二产程中从胎儿先露部采血所得到的pH值与胎儿中心血几乎相同。

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The reliability of pH-values in fetal blood samples - A study of the second stage.胎儿血样中pH值的可靠性——第二阶段研究
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