Carpenter J P, Golden M A, Barker C F, Holland G A, Baum R A
Department of Surgery, University of Pennsylvania School of Medicine, Philadelphia, USA.
J Vasc Surg. 1996 Mar;23(3):483-9. doi: 10.1016/s0741-5214(96)80015-2.
Magnetic resonance angiography (MRA) is a noninvasive vascular imaging technique that is more sensitive than contrast arteriography (CA) for the detection of patent distal runoff vessels. This technique has facilitated performance of MRA-directed bypass procedures for patients who were believed not to be bypass candidates because of the absence of a suitable target vessel on the preoperative CA. The fate of bypasses to these angiographically occult runoff vessels is unknown, however, and it has been proposed that patients with angiographically occult runoff may have aggressive occlusive disease, rendering bypass procedures ultimately futile.
Between April 1992 and February 1995, 212 autogenous vein infrageniculate bypasses were performed for limb-salvage indications, 22 (12%) to angiographically occult runoff vessels. Results of bypasses performed to angiographically occult vessels were compared with those of bypasses to CA-detected runoff vessels. Life-table analysis of graft-patency and limb-salvage rates was performed.
The accuracy of the MRA-predicted patency of angiographically occult vessels was confirmed in every case by the operative findings. Life-table analysis revealed no significant difference in primary graft patency (p > 0.05) or limb-salvage (p > 0.05) rates between patients with bypasses to runoff vessels seen by MRA alone. At 35 months after surgery, the primary graft patency rate was 68% for bypasses to CA-detected vessel bypass and 67% for MRA-detected vessels. The limb salvage rate was 83% for CA-detected vessel bypass patients and 78% for patients with angiographically occult runoff.
MRA can accurately identify patent runoff vessels not visualized by CA. Results of bypasses performed to angiographically occult runoff vessels are similar to those of bypasses performed to vessels detected by CA. MRA should be performed in patients in whom CA fails to reveal runoff vessels suitable for use in a limb-salvage procedure. The greater sensitivity of MRA may facilitate successful bypass surgery and improve the overall limb-salvage rate.
磁共振血管造影(MRA)是一种非侵入性血管成像技术,在检测通畅的远端流出血管方面比造影动脉造影(CA)更敏感。对于那些因术前CA未发现合适靶血管而被认为不适合进行旁路手术的患者,这项技术推动了MRA引导下的旁路手术的开展。然而,这些血管造影隐匿性流出血管的旁路手术效果尚不清楚,有人提出血管造影隐匿性流出血管的患者可能患有侵袭性闭塞性疾病,导致旁路手术最终徒劳无功。
在1992年4月至1995年2月期间,为挽救肢体进行了212例自体静脉膝下旁路手术,其中22例(12%)是针对血管造影隐匿性流出血管。将针对血管造影隐匿性血管进行的旁路手术结果与针对CA检测到的流出血管进行的旁路手术结果进行比较。对移植物通畅率和肢体挽救率进行生存分析。
手术结果证实了MRA预测的血管造影隐匿性血管通畅的准确性。生存分析显示,仅通过MRA发现流出血管并进行旁路手术的患者,其原发性移植物通畅率(p>0.05)或肢体挽救率(p>0.05)无显著差异。术后35个月,针对CA检测到的血管进行旁路手术的原发性移植物通畅率为68%,针对MRA检测到的血管为67%。CA检测到血管的旁路手术患者的肢体挽救率为83%,血管造影隐匿性流出血管患者为78%。
MRA可以准确识别CA未显示的通畅流出血管。针对血管造影隐匿性流出血管进行的旁路手术结果与针对CA检测到的血管进行的旁路手术结果相似。对于CA未能发现适合用于肢体挽救手术的流出血管的患者,应进行MRA检查。MRA更高的敏感性可能有助于成功进行旁路手术并提高总体肢体挽救率。