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1992年新南威尔士州与海洛因相关的死亡:毒理学发现及情况

Heroin-related deaths in New South Wales, 1992: toxicological findings and circumstances.

作者信息

Zador D, Sunjic S, Darke S

机构信息

Drug and Alcohol Services, Division of Public Health, South Western Sydney Area Health Service, NSW.

出版信息

Med J Aust. 1996 Feb 19;164(4):204-7. doi: 10.5694/j.1326-5377.1996.tb94136.x.

Abstract

OBJECTIVE

To describe the circumstances of death and toxicological findings in all heroin-related deaths in New South Wales in 1992.

DESIGN

Coronial files of all cases of heroin-related deaths were reviewed. A standardised form was used to collect information on sociodemographics, history of drug use, circumstances of death, and results of toxicological analysis for each case.

RESULTS

152 heroin-related deaths were identified. Subjects had a mean age of 29.7 years, 82% were male, and 98% were not enrolled in a methadone treatment program at the time of their deaths. Deaths occurred in the home environment in 68% of cases and in the company of at least one other person in 58%. There was intervention before the subject's death in only 21% of cases. Two or more drug classes were detected in 71% of subjects; alcohol was detected in 45%, with a mean blood alcohol concentration of 0.14 g/100mL.

CONCLUSIONS

Fatal heroin overdose is potentially preventable. Educating users about the risks of co-administering alcohol and other depressant drugs with heroin, the comparative safety of injecting heroin in the company of others and the need to call for intervention sooner may reduce the frequency of heroin-related deaths.

摘要

目的

描述1992年新南威尔士州所有与海洛因相关死亡案例的死亡情况及毒理学发现。

设计

对所有与海洛因相关死亡案例的死因裁判档案进行审查。使用标准化表格收集每个案例的社会人口统计学信息、吸毒史、死亡情况以及毒理学分析结果。

结果

共确定了152例与海洛因相关的死亡案例。死者的平均年龄为29.7岁,82%为男性,98%在死亡时未参加美沙酮治疗项目。68%的死亡案例发生在家庭环境中,58%的案例是在至少有一人陪伴的情况下死亡。只有21%的案例在死者死亡前有过干预措施。71%的死者体内检测出两种或更多种类的毒品;45%的死者体内检测出酒精,平均血液酒精浓度为0.14 g/100mL。

结论

致命性海洛因过量服用有可能预防。对使用者进行教育,告知他们海洛因与酒精及其他抑制性药物共同使用的风险、在他人陪伴下注射海洛因的相对安全性以及尽早寻求干预的必要性,可能会降低与海洛因相关的死亡频率。

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