Engle J
HIV Research Clinic, Warren Grant Magnuson Clinical Center, National Institutes of Health, Washington, D.C., USA.
Nurs Clin North Am. 1996 Mar;31(1):15-23.
Even if there were antiretrovirals developed that could completely eliminate HIV from the body, it is thought that immune-based therapy would still be necessary. Pervasive damage occurs in the immune system even in early stages of the disease, and this damage would not be corrected by antiretrovirals. Several different types of immune-based therapies are presented in this article; some have been successful, and some have not been successful. All have been important, however, in increasing the knowledge base of HIV pathogenesis and in narrowing the options that might rebuild the immune system and, thereby, reverse this pathology.
即使研发出了能将艾滋病毒从体内完全清除的抗逆转录病毒药物，人们认为基于免疫的疗法仍将是必要的。即便在疾病早期，免疫系统就已出现广泛损伤，而这种损伤无法通过抗逆转录病毒药物得到纠正。本文介绍了几种不同类型的基于免疫的疗法；有些取得了成功，有些则未成功。然而，所有这些疗法在增加艾滋病毒发病机制的知识储备以及缩小可能重建免疫系统从而逆转这种病理状况的选择范围方面都具有重要意义。
