Hanna N N, O'Donnell K, Wolfe G R
Department of Surgery, St. Elizabeth's Medical Center of Boston, Tufts University School of Medicine, Massachusetts 02135, USA.
J Surg Oncol. 1996 Feb;61(2):159-62. doi: 10.1002/(SICI)1096-9098(199602)61:2<159::AID-JSO13>3.0.CO;2-4.
Metastasis to the breast is uncommon, with an incidence of 0.5-3%. Alveolar soft part sarcoma is rare, accounting for < 1% of malignant soft tissue tumors, which are themselves unusual. Excluding contralateral breast and hematologic malignant disease, the primary lesion in most cases of metastasis to the breast is melanoma, small cell carcinoma of the lung, or ovarian carcinoma, although rhabdomyosarcoma is the most common primary tumor in children. We describe a 26-year-old woman with no history of malignant disease who presented with two masses in the right breast that clinical evaluations and ultrasonography indicated were fibroadenomas. Pathological studies after excisional biopsy, however, indicated alveolar soft part sarcoma. Subsequent computed tomography showed the primary tumor in the anterior left thigh and multiple bilateral lung metastases. Because of the presence of distant metastases, the patient was treated with chemotherapy.
乳腺转移并不常见，发生率为0.5%-3%。肺泡软部肉瘤罕见，占恶性软组织肿瘤的比例不到1%，而恶性软组织肿瘤本身就不常见。排除对侧乳腺和血液系统恶性疾病，大多数乳腺转移病例的原发灶是黑色素瘤、肺小细胞癌或卵巢癌，不过横纹肌肉瘤是儿童最常见的原发肿瘤。我们报告一名26岁无恶性疾病史的女性，她右侧乳腺出现两个肿块，临床评估和超声检查显示为纤维腺瘤。然而，切除活检后的病理研究表明是肺泡软部肉瘤。随后的计算机断层扫描显示原发肿瘤位于左大腿前部，并伴有双侧肺部多发转移。由于存在远处转移，该患者接受了化疗。
