Cusick W, Bork M, Fabri B, Benn P, Rodis J F, Buttino L
Center for Human Reproduction, Division of Maternal-Fetal Medicine, Chicago, IL 60610, USA.
Prenat Diagn. 1995 Nov;15(11):1078-81. doi: 10.1002/pd.1970151115.
A 27-year-old gravida 4, para 3 was found to have anhydramnios at 14 weeks' gestation following a size/date discrepancy noted at her routine prenatal visit. A detailed ultrasound revealed multiple fetal anomalies including congenital heart defect, chest hypoplasia, and bilateral dysplastic kidneys. Karyotype revealed trisomy 16 in 15/15 cells from a tissue specimen obtained from the fetal cord insertion site following elective pregnancy termination.
一名27岁、孕4产3的孕妇，在常规产前检查时发现孕周与宫高腹围不符，妊娠14周时被诊断为羊水过少。详细超声检查显示胎儿存在多种异常，包括先天性心脏缺陷、胸部发育不全和双侧肾发育不良。在选择性终止妊娠后，从胎儿脐带附着处获取的组织标本进行核型分析，结果显示15个细胞中有15个为16三体。
