Saidi M, Nadjmabadi M, Tarbiat S
Anaesthesist. 1977 Apr;26(4):184-6.
The serum potassium levels were determined in 2 groups. The first group (40 children) was treated preoperatively with digitalis and diuretics. The second group (20 children) received none of these drugs and served as a control group. During the period of bypass, all patients received potassium-chloride, 1 m Eq/per Kg/h, which was infused into the heartlung machine. The serum potassium levels were determined before, during and after extracorporeal circulation. The first group showed a significant decrease in the serum potassium level during and after the bypass. The lower serum potassium levels (less than 4 m Eq/L) had to be corrected by injection of potassium aspartate. In the second group, an increased serum potassium level was observed. It is advisable to reduce the amount of potassium administered by half in patients not pretreated with digitalis and diuretics. In those who have been pretreated with these drugs, hypokalaemia should be avoided by frequent serum potassium estimation and potassium administration if needed.
测定了两组患者的血清钾水平。第一组(40名儿童)术前接受洋地黄和利尿剂治疗。第二组(20名儿童)未使用这些药物,作为对照组。在体外循环期间,所有患者均接受氯化钾,以1毫当量/千克/小时的速度注入心肺机。在体外循环前、期间和之后测定血清钾水平。第一组在体外循环期间和之后血清钾水平显著下降。较低的血清钾水平(低于4毫当量/升)必须通过注射门冬氨酸钾来纠正。在第二组中,观察到血清钾水平升高。对于未接受洋地黄和利尿剂预处理的患者,建议将钾的给药量减半。对于已经接受这些药物预处理的患者,应通过频繁测定血清钾水平并在需要时补充钾来避免低钾血症。