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体外循环手术前、手术期间及手术后用放射免疫分析法测定血清洋地黄糖苷浓度(作者译)

[Determination of serum-digitalisglycoside concentrations by radioimmunoassay before, during and after operations with extracorporal circulation (author's transl)].

作者信息

Stunkat R, Seboldt H, Hoffmeister H E, Haasis R, Larbig D, Kochsiek K

出版信息

Thoraxchir Vask Chir. 1975 Aug;23(4):350-3. doi: 10.1055/s-0028-1096980.

Abstract

In 13 adult patients serum-glycoside concentrations, renal glycoside elimination and endogenic creatinine clearance were determined before, during and in the first 4 days following the operation. A postoperative digitalis cumulation has not been seen. But there was a diminished digitalis tolerance in the immediate postoperative phase. Two patients got ventricular bigeminus. The low potassium values at the same time may possibly affect the sensitivity of digitalis.

摘要

对13例成年患者在手术前、手术期间及术后第1天至第4天测定了血清糖苷浓度、肾脏糖苷清除率和内生肌酐清除率。未观察到术后洋地黄蓄积现象。但在术后即刻出现洋地黄耐受性降低。2例患者出现室性二联律。同时低钾血症可能影响洋地黄的敏感性。

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