Wauters J P
Division of Nephrology, CHUV Lausanne, Switzerland.
Clin Nephrol. 1995 Nov;44 Suppl 1:S19-23.
Even if the definition of the term biocompatibility is still not clear, many of its manifestations during hemodialysis are now well documented. Some of their pathophysiological and clinical implications are briefly reviewed. It appears that not only the dialyzer membrane but also the extracorporeal circuit as a whole should be considered. Biological and clinical evidences confirm that the present more biocompatible membranes seem associated with better acute and long-term tolerance of hemodialysis when compared to less biocompatible membranes. However, potential side-effects such as backfiltration or drug interactions should not be overlooked.
尽管生物相容性这一术语的定义仍不明确，但目前其在血液透析过程中的许多表现已有充分记录。本文简要回顾了其中一些病理生理和临床意义。似乎不仅透析器膜，而且整个体外循环都应予以考虑。生物学和临床证据证实，与生物相容性较差的膜相比，目前生物相容性更好的膜似乎与血液透析更好的急性和长期耐受性相关。然而，诸如反滤过或药物相互作用等潜在副作用不应被忽视。
