Ratnanather J T, Zhi M, Brownell W E, Popel A S
Department of Otolaryngology-Head and Neck Surgery and Center for Hearing Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205-2196, USA.
J Acoust Soc Am. 1996 Feb;99(2):1025-8. doi: 10.1121/1.414631.
Outer hair cells (OHCs) were subjected to three different hypo-osmotic challenges which induced shape changes in OHCs. The longitudinal and circumferential strains, epsilon z and epsilon c, respectively, were extracted from a morphometric analysis of video images of the cells. A value of epsilon z/epsilon c = -0.72 was obtained and was found to be independent of the applied osmotic gradient. Using an elastic isotropic membrane model for the OHC lateral wall, the ratio of the elastic shear modulus mu to the elastic area expansion modulus K was calculated yielding a value of 0.054. The contribution of this ratio to OHC mechanics is discussed.
外毛细胞（OHCs）经受了三种不同的低渗挑战，这些挑战诱导了外毛细胞的形状变化。纵向应变和周向应变，分别为εz和εc，是从细胞视频图像的形态计量分析中提取的。得到εz/εc = -0.72的值，并且发现该值与施加的渗透梯度无关。使用外毛细胞侧壁的弹性各向同性膜模型，计算了弹性剪切模量μ与弹性面积膨胀模量K的比值，得到的值为0.054。讨论了该比值对外毛细胞力学的贡献。
