Shimada Y
Dept. of Medical Oncology, National Cancer Center Hospital, Japan.
Gan To Kagaku Ryoho. 1996 Jan;23(2):136-40.
Well-designed clinical trials have been the only ways to answer many questions as to the "uncertainty" of cancer treatment. However, general physicians and mass media have not been willing to accept clinical trials because they were experiments on patients. In order to break through the present bottleneck it is very important to recognize the clinical significance of clinical trials by physicians themselves and to establish a system for reviewing and managing protocol study and for collecting clinical data. It is also important to obtain honest informed consent from patients tested in clinical trials. To accumulate the scientific evidences from clinical trials was the best way to achieve significant advances in cancer therapy.
精心设计的临床试验一直是解答许多关于癌症治疗“不确定性”问题的唯一途径。然而,普通医生和大众媒体一直不愿意接受临床试验,因为它们是在患者身上进行的实验。为了突破当前的瓶颈,医生自身认识到临床试验的临床意义,建立一个用于审查和管理方案研究以及收集临床数据的系统非常重要。在临床试验中获得患者真实的知情同意也很重要。积累来自临床试验的科学证据是在癌症治疗方面取得重大进展的最佳途径。