Different cardiac myosin isoforms exhibit equal force-generating ability in vitro.
作者信息
Sugiura S, Kobayakawa N, Momomura S, Chaen S, Omata M, Sugi H
机构信息
The Second Department of Internal Medicine, School of Medicine, University of Tokyo, Japan.
出版信息
Biochim Biophys Acta. 1996 Feb 15;1273(2):73-6. doi: 10.1016/0005-2728(95)00149-2.
PMID:8611591
Abstract
We measured forces generated by myosin molecules and a single actin filament using an optical trap system. The force per unit length of actin filament did not differ significantly between cardiac myosin isoforms. V1 and V3. This indicates that the ability to generate force is equal between V1 and V3, despite their difference in the unloaded sliding velocity past actin.
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