天然DNA中分子间相互作用的介电研究。

Dielectric studies of intermolecular interactions in native DNA.

作者信息

Bone S, Lee R S, Hodgson C E

机构信息

Institute of Molecular and Biomolecular Electronics, University of Wales, Bangor, Gwynedd, UK.

出版信息

Biochim Biophys Acta. 1996 Apr 10;1306(1):93-7. doi: 10.1016/0167-4781(95)00232-4.

DOI:10.1016/0167-4781(95)00232-4

PMID:8611629

Abstract

The concentration dependence of the high frequency dielectric dispersion exhibited by solutions of DNA and the sensitivity of this to the ionic strength of the solution are described. Dielectric data obtained are consistent with a model involving the fluctuation of counterions along short segments of the DNA chain. The concentration and ion strength dependencies are discussed in terms of intermolecular interactions which are considered responsible for the existence of structure in DNA solutions.

摘要

描述了DNA溶液所呈现的高频介电色散的浓度依赖性以及其对溶液离子强度的敏感性。所获得的介电数据与一个涉及抗衡离子沿DNA链短片段波动的模型一致。从分子间相互作用的角度讨论了浓度和离子强度的依赖性，这些相互作用被认为是DNA溶液中结构存在的原因。