Vidovic M, Hill C E
Division of Neuroscience, John Curtin School of Medical Research, Australian National University, Canberra, Australia.
Brain Res Dev Brain Res. 1995 Nov 21;89(2):309-13. doi: 10.1016/0165-3806(95)00118-w.
We have examined the developmental profile of the alpha-1 and alpha-2 adrenergic receptor mRNA expression in the rat iris. The expression of the six mRNAs was studied using reverse transcription-polymerase chain reaction. At 4 weeks, the dominant mRNA transcripts in the rat iris were alpha-1B, alpha-1C and alpha-2A. This pattern of alpha adrenoceptor expression was seen from birth, throughout development, and maintained into old age.