Lipton J H, Gospodarowicz M, Reingold S
Department of Medicine, Princess Margaret Hospital/Ontario Cancer Institute, Toronto, Canada.
Hematol Oncol. 1996 Mar;14(1):29-31. doi: 10.1002/(SICI)1099-1069(199603)14:1<29::AID-HON561>3.0.CO;2-J.
A 26-year-old man developed myelodysplasia rapidly progressing to acute myelomonocytic leukemia 3 years after receiving three cycles of ABVD chemotherapy and upper mantle and upper abdomen radiotherapy for stage IA Hodgkin's disease. This represents the fourth such case reported. The risk of secondary AML after ABVD or radiation therapy is discussed.
一名26岁男性在接受三个周期的ABVD化疗以及针对IA期霍奇金淋巴瘤的上半腹和上腹部放疗3年后,迅速发展为骨髓发育异常并进展为急性粒单核细胞白血病。这是报道的第四例此类病例。文中讨论了ABVD化疗或放射治疗后发生继发性急性髓系白血病的风险。