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儿童结核性脑膜炎——细菌学确诊病例的临床特征、死亡率和发病率

Tuberculous meningitis in children--clinical profile, mortality and morbidity of bacteriologically confirmed cases.

作者信息

Thilothammal N, Krishnamurthy P V, Banu K, Ratnam S R

机构信息

Clinical Epidemiology Unit, Institute of Child Health and Hospital for

出版信息

Indian Pediatr. 1995 Jun;32(6):641-7.

PMID:8613332
Abstract

One hundred and seven cases of tuberculous meningitis were registered as a part of a case-control study during the period 1990-1992. The CSF of all cases was positive for culture and/or smear for acid fast bacilli. Children were examined at the time of admission and at the time of discharge and they were contacted at the end of 1 year. Clinical picture, mortality and morbidity were analyzed. Mortality of children during the first month of illness was 22%. Some of the cases presented as acute neurological illness. We also came across CSF picture with minimal cytological and biochemical changes but with positive culture results.

摘要

在1990年至1992年期间,作为一项病例对照研究的一部分,登记了107例结核性脑膜炎病例。所有病例的脑脊液经培养和/或抗酸杆菌涂片检查均呈阳性。在入院时和出院时对儿童进行检查,并在1年末与他们联系。对临床表现、死亡率和发病率进行了分析。患病第一个月儿童的死亡率为22%。一些病例表现为急性神经疾病。我们还遇到了脑脊液检查结果细胞学和生化变化极小但培养结果呈阳性的情况。

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