Okamoto H, Ogawara T, Arihara F, Kobayashi K, Inoue S, Nagahori K, Yamamoto M, Sekikawa T, Matsumoto Y
Department of Health Care Center, Yamanashi Prefectural Welfare Federation of Agricultural Co-operatives.
Jpn J Cancer Res. 1996 Mar;87(3):317-23. doi: 10.1111/j.1349-7006.1996.tb00223.x.
We retrospectively analyzed the records for 34,474 women who participated in mass screening for breast cancer by physical examination with or without ultrasonography (US) at Yamanashi Health Care Center between April, 1989 and March, 1994 to evaluate the usefulness of US in mass screening. In one group (15,935 women) conventional physical examination with inspection and palpation alone had been performed, and in another (18,539 women) both conventional physical and US examinations were performed. Breast cancer was detected in 27 of the women (0.08% of the total group screened), 22 of whom were in the group examined by US; moreover, 16 of these 22 women had early breast cancer, which was a non-palpable tumor in 13. Half of the 22 women were examinees under the age of 50 years. Of the 22 tumors detected in the groups examined by US, 16 (73%) were early breast cancer. The overall detection of early breast cancer (0.09%) in the US group was significantly higher than that (0.01%) in the group examined by conventional methods (P < 0.05). Of the tumors detected in the US group, 59.1% were non-palpable. These results suggest that early and non-palpable breast cancer can be detected using US, and the incidence of detection of such tumors in women under the age 50 years is increased in mass screening including US examination. This examination is effective in mass screening for breast cancer, especially for early and non-palpable breast cancer tumors.
我们回顾性分析了1989年4月至1994年3月期间在山梨县医疗保健中心参加乳腺癌群体筛查的34474名女性的记录，这些女性接受了体格检查，部分还接受了超声检查（US），以评估超声在群体筛查中的作用。一组（15935名女性）仅进行了包括视诊和触诊的传统体格检查，另一组（18539名女性）则同时进行了传统体格检查和超声检查。在这些女性中，共检测出27例乳腺癌（占筛查总人数的0.08%），其中22例在接受超声检查的组中；此外，这22例女性中有16例为早期乳腺癌，其中13例为不可触及的肿瘤。22例女性中有一半年龄在50岁以下。在接受超声检查的组中检测出的22例肿瘤中，16例（73%）为早期乳腺癌。超声检查组中早期乳腺癌的总体检出率（0.09%）显著高于传统方法检查组（0.01%）（P<0.05）。在超声检查组中检测出的肿瘤，59.1%为不可触及的。这些结果表明，使用超声可以检测出早期和不可触及的乳腺癌，并且在包括超声检查的群体筛查中，50岁以下女性中此类肿瘤的检出率有所增加。这项检查在乳腺癌群体筛查中有效，尤其是对于早期和不可触及的乳腺癌肿瘤。
