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[结节病伴多发支气管狭窄及肺部肿瘤样改变]

[Sarcoidosis with multiple bronchial stenoses and neoplastic changes in the lungs].

作者信息

Meleniewska-Maciszewska A

机构信息

I Kliniki Gruźlicy i Chorób Płuc Instytutu Gruźlicy i Chorób Płuc, Warszawie.

出版信息

Pneumonol Pol. 1990 Nov-Dec;58(11-12):629-33.

PMID:8614655
Abstract

A case report of a 45 year old female with a high suspicion of a lung tumor based on radiological and bronchoscopic findings is presented. Typical sarcoid changes were seen in biopsies from bronchial mucosa. Steroid therapy was instituted but due to intolerance had to be terminated. The patient was treated with chlorambucil, cyclophosphamide and azathioprine. Therapy was monitored with bronchoscopy. The best response was seen after steroid therapy, less to chlorambucil and cyclophosphamide. Azathioprine was least effective.

摘要

本文报告了一例45岁女性病例,根据影像学和支气管镜检查结果高度怀疑患有肺部肿瘤。支气管黏膜活检可见典型的结节病改变。开始使用类固醇治疗,但因不耐受而不得不终止。患者接受了苯丁酸氮芥、环磷酰胺和硫唑嘌呤治疗。通过支气管镜监测治疗情况。类固醇治疗后效果最佳,苯丁酸氮芥和环磷酰胺的效果次之。硫唑嘌呤效果最差。

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