Halweg H, Korzeniewska-Koseła M, Podsiadło B, Krakówka P
Kliniki Gruźlicy i Chorób Płuc, Warszawie.
Pneumonol Pol. 1990 Sep-Oct;58(9-10):544-8.
Here is presented a case of woman treated by immunosuppressive preparations because of systemic lupus erythematosus with ski manifestations as tubercles and ulcerations on skin of trunk and extremities. On the basis of histological examination of tubercle skin specimens and mycological examinations of material obtained from skin ulcerations cryptococcosis was diagnosed. Disease was limited to skin that was an entry of infection. Patient was treated by Amphotericin B administered intravenously and Flucitosine per os. Amphotericin B was also applied topically. The results of cultures became gradually negative, up to total disappearance of fungus cells in direct specimens, prepared from examined material. After treatment continuing for 5 months only discoloured scars were observed on sick skin.
本文介绍了一例因系统性红斑狼疮接受免疫抑制治疗的女性病例，其皮肤表现为躯干和四肢皮肤出现结节和溃疡。根据结节皮肤标本的组织学检查以及皮肤溃疡取材的真菌学检查，诊断为隐球菌病。疾病仅限于皮肤，此处为感染入口。患者接受了静脉注射两性霉素B和口服氟胞嘧啶治疗。两性霉素B也进行了局部应用。培养结果逐渐转阴，直至从检查材料制备的直接标本中真菌细胞完全消失。治疗持续5个月后，患病皮肤上仅观察到色素沉着的瘢痕。
