Grazioli L, Olivetti L, Stanga C, Matricardi L, Fugazzola C, Benzi F, Bonardelli S, Scolari F, Sandrini S
Cattedra di Radiologia, Università de Brescia.
Radiol Med. 1996 Jan-Feb;91(1-2):101-6.
Artery stenosis in the transplanted kidney is the most frequent vascular complication; hypertension onset or worsening may be associated and, at an end stage, also renal insufficiency. The diagnosis must be early and accurate and provide guidelines for medical, interventional or surgical therapy. To assess the diagnostic reliability or MRA, 27 patients were examined. On the basis of clinical, biochemical, pharmacological (Captopril test) and instrumental (color-Doppler US) examinations, the artery of the transplanted kidney was considered normal in 6 patients and stenotic in 21. In the control group, MRA results were in agreement with color-Doppler findings. On the contrary, in 8 of 21 abnormal conditions, the two techniques were in disagreement. Digital angiography, considered as the gold standard, was performed in any questionable case, confirming a slight overestimation of the stenoses by MRA (3 cases) and 2 false positives by color-Doppler US. The authors believe color-Doppler US to be a reliable technique for screening stenosed arteries in the transplanted kidney. MRA is proposed as a complementary investigation useful to define stenosis type and to provide guidelines for treatment.
移植肾动脉狭窄是最常见的血管并发症;高血压的发作或加重可能与之相关,在终末期还可能伴有肾功能不全。诊断必须早期且准确,并为药物、介入或手术治疗提供指导。为评估磁共振血管造影(MRA)的诊断可靠性,对27例患者进行了检查。根据临床、生化、药理学(卡托普利试验)和影像学(彩色多普勒超声)检查,6例患者的移植肾动脉被认为正常,21例存在狭窄。在对照组中,MRA结果与彩色多普勒检查结果一致。相反,在21例异常情况中的8例中,两种技术结果不一致。对于任何有疑问的病例,均进行了被视为金标准的数字血管造影,证实MRA对狭窄程度略有高估(3例),彩色多普勒超声有2例假阳性。作者认为彩色多普勒超声是筛查移植肾动脉狭窄的可靠技术。建议将MRA作为一项补充检查,有助于明确狭窄类型并为治疗提供指导。