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急性结节病关节炎:预后良好?对49例患者的回顾性调查及文献复习

Acute sarcoid arthritis: a favourable outcome? A retrospective survey of 49 patients with review of the literature.

作者信息

Gran J T, Bøhmer E

机构信息

Department of Rheumatology, Central Hospital of Aust Agder, Arendal, Norway.

出版信息

Scand J Rheumatol. 1996;25(2):70-3. doi: 10.3109/03009749609069210.

Abstract

Forty-nine patients, 30 males and 19 females with acute sarcoid arthritis admitted to three different hospitals in Norway were studied retrospectively. All patients had peripheral arthritis and hilar adenopathy, and 87.8% also presented with erythema nodosum (EN). Mean duration of arthritis was 3.7 months (0.5-12 months), but in 26% of the cases, duration of the inflammatory joint disease exceeded three months. Radiological bony erosions were not seen. Two patients had recurrence of acute sarcoid arthritis, 14 months and 10 years after the initial episode, respectively. Two other patients developed chronic myalgia and fibromyalgia. Four patients, one female and three males, developed chronic pulmonal sarcoidosis. Of these, two patients had simultaneous onset of acute sarcoid arthritis and parenchymal disease while two patients developed chronic lung disease three months after onset of acute sarcoid arthritis. We thus tentatively suggest that although acute sarcoid arthritis is usually a self-limiting joint disease, recurrences may occasionally occur and some cases develop chronic sarcoidosis of the lungs.

摘要

对挪威三家不同医院收治的49例急性结节病关节炎患者进行了回顾性研究,其中男性30例,女性19例。所有患者均有外周关节炎和肺门淋巴结肿大,87.8%的患者还出现结节性红斑(EN)。关节炎的平均病程为3.7个月(0.5 - 12个月),但在26%的病例中,炎症性关节病的病程超过3个月。未发现放射学骨侵蚀。两名患者分别在初次发作后14个月和10年出现急性结节病关节炎复发。另外两名患者发展为慢性肌痛和纤维肌痛。四名患者,一名女性和三名男性,发展为慢性肺部结节病。其中,两名患者急性结节病关节炎与实质性疾病同时发病,两名患者在急性结节病关节炎发病三个月后发展为慢性肺部疾病。因此,我们初步认为,虽然急性结节病关节炎通常是一种自限性关节疾病,但偶尔可能会复发,部分病例会发展为慢性肺部结节病。

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