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西班牙塞哥维亚短暂性脑缺血发作和轻度缺血性卒中的发病率。

Incidence of transient ischemic attacks and minor ischemic strokes in Segovia, Spain.

作者信息

Sempere A P, Duarte J, Cabezas C, Clavería L E

机构信息

Department of Neurology, Segovia General Hospital, Spain.

出版信息

Stroke. 1996 Apr;27(4):667-71. doi: 10.1161/01.str.27.4.667.

Abstract

BACKGROUND AND PURPOSE

The aim of this study was to determine the incidence of transient ischemic attacks (TIAs) and minor ischemic strokes (MISs) in Segovia, Spain.

METHODS

A 2-year prospective community-based register of TIAs and MISs established in Segovia from February 16, 1992, to February 15, 1994. Every patient underwent underwent a complete clinical evaluation and cranial CT scan. Sex- and age-specific incidence rates with 95% confidence intervals (CIs) were calculated for all ages.

RESULTS

The total series included 235 patients; 103 suffered TIAs and 132 suffered MISs. Mean age was 70.8 years (range, 29 to 96 years); 92 were women and 143 were men. The crude annual incidence was 0.80/1000 (95% CI, 0.70 to 0.90): 0.35/1000 (95% CI, 0.28 to 0.42) for TIAs and 0.45/1000 (95% CI, 0.37 to 0.53) for MISs. The incidence of TIAs and MISs increased with age. Approximately 78 of TIAs and MISs were in the carotid distribution, 19% were vertebrobasilar, and 3% were considered of uncertain vascular distribution. Cranial CT scan was performed in all patients. CT showed cerebral infarcts in 30.1% (31/103; 95% CI, 21% to 39%) of TIAs and 70% (92/132; 95% CI, 62% to 78%) of MISs (P<.00001).

CONCLUSIONS

Our study is the first community-based register that provides sex-and age-specific rates for MISs and in which a CT scan was obtained in all patients. The incidence of TIAs in Segovia is comparable to that in other previous similar studies.

摘要

背景与目的

本研究旨在确定西班牙塞哥维亚短暂性脑缺血发作(TIA)和轻度缺血性卒中(MIS)的发病率。

方法

1992年2月16日至1994年2月15日在塞哥维亚建立了一个为期2年的基于社区的TIA和MIS登记册。每位患者均接受了全面的临床评估和头颅CT扫描。计算了所有年龄段的性别和年龄特异性发病率及95%置信区间(CI)。

结果

该系列研究共纳入235例患者;103例发生TIA,132例发生MIS。平均年龄为70.8岁(范围29至96岁);女性92例,男性143例。年粗发病率为0.80/1000(95%CI,0.70至0.90):TIA为0.35/1000(95%CI,0.28至0.42),MIS为0.45/1000(95%CI,0.37至0.53)。TIA和MIS的发病率随年龄增长而增加。约78%的TIA和MIS发生在颈动脉分布区,19%在椎基底动脉分布区,3%的血管分布情况不确定。所有患者均进行了头颅CT扫描。CT显示30.1%(31/103;95%CI,21%至39%)的TIA和70%(92/132;95%CI,62%至78%)的MIS存在脑梗死(P<0.00001)。

结论

我们的研究是首个基于社区的登记册,提供了MIS的性别和年龄特异性发病率,且所有患者均进行了CT扫描。塞哥维亚TIA的发病率与之前其他类似研究相当。

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