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意大利贝卢诺省短暂性脑缺血发作的发病率。一项基于社区研究的第一年结果。

Incidence of transient ischemic attacks in the Belluno Province, Italy. First-year results of a community-based study.

作者信息

Lauria G, Gentile M, Fassetta G, Casetta I, Agnoli F, Andreotta G, Barp C, Caneve G, Cavallaro A, Cielo R, Mongillo D, Mosca M, Olivieri P

机构信息

Section of Neuroepidemiology, University of Ferrara, Italy.

出版信息

Acta Neurol Scand. 1996 Apr;93(4):291-6. doi: 10.1111/j.1600-0404.1996.tb00523.x.

Abstract

OBJECTIVES

This study formed part of a larger prospective population-based survey on cerebrovascular diseases and aimed to provide reliable and comparable results on TIA incidence and on related risk factors, which could supply investigation objectives and support information for primary and secondary prevention.

MATERIAL AND METHODS

We undertook a prospective population-based study in the province of Belluno, an area located in the North-East of Italy where 211,389 people live, utilizing all the possible case-collection sources available in the territory.

RESULTS

In the first year of the study (June 1, 1992 to May 31, 1993) 271 patients with a diagnosis of transient ischemic attack were recruited. Among these, we recorded 171 cases of new TIAs. The crude annual incidence rate for new TIAs was 0.80 per 1000, 0.73 per 1000 for men and 0.87 per 1000 for women. After adjustment to the European population, the overall incidence rate decreased to 0.58 per 1000 inhabitants per year. The mean age of new TIA patients was 73.91 years and females were significantly older than males (p < 0.001). A CT scan disclosed an infarct in 21 new TIA patients.

CONCLUSION

Our first-year results on new TIAs incidence did not differ from the findings reported in previous population-based studies performed throughout the world and support data as to risk factors for TIA.

摘要

目的

本研究是一项关于脑血管疾病的大型前瞻性人群调查的一部分,旨在提供关于短暂性脑缺血发作(TIA)发病率及相关危险因素的可靠且可比的结果,可为一级和二级预防提供调查目标及支持信息。

材料与方法

我们在意大利东北部的贝卢诺省开展了一项前瞻性人群研究,该地区有211,389人居住,利用该地区所有可能的病例收集来源。

结果

在研究的第一年(1992年6月1日至1993年5月31日),招募了271例诊断为短暂性脑缺血发作的患者。其中,我们记录了171例新的TIA病例。新TIA的粗年发病率为每1000人0.80例,男性为每1000人0.73例,女性为每1000人0.87例。经欧洲人群校正后,总发病率降至每年每1000名居民0.58例。新TIA患者的平均年龄为73.91岁,女性明显比男性年龄大(p < 0.001)。CT扫描显示21例新TIA患者有梗死灶。

结论

我们关于新TIA发病率的第一年结果与全球此前基于人群的研究所报告的结果无异,并支持有关TIA危险因素的数据。

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