Castella J, Buj J, Puzo C, Antón P A, Burgués C
Departament de Pneumologia, Hospital Sta. Creu i St. Pau, Barcelona, Spain.
Ann Oncol. 1995;6 Suppl 3:S21-4. doi: 10.1093/annonc/6.suppl_3.s21.
Transbronchial needle aspiration (TBNA) has been used in diagnosis and staging of bronchogenic carcinoma. However, its true effectiveness seems uncertain and some models of needles are expensive. The aim of this study was to procure new experiences on this method. TBNA was performed in 194 patients with bronchogenic carcinomas. Two models of cheap, re-usable, cytological needles were used. In diagnostic application, TBNA was positive in 34 of 39 (87%) central tumors and in 31 of 45 (69%) peripheral nodules or masses. In 19 patients, TBNA was the only positive sample. In staging application, TBNA was positive in 41 of the 90 cases (46%) in which the spread of the tumor compressed the wall of the airway. When the trachea or bronchus was endoscopically normal at the site of the puncture, TBNA was only positive in 3 of 20 cases (15%). These results suggest that TBNA is effective as a diagnostic tool. However, it appears to be less effective in staging, where the attainment of a good yield with TBNA probably demands a positive computed tomography and the use of a histological needle.
经支气管针吸活检术(TBNA)已用于支气管源性癌的诊断和分期。然而,其真正的有效性似乎并不确定,而且一些型号的针价格昂贵。本研究的目的是获取关于该方法的新经验。对194例支气管源性癌患者进行了TBNA。使用了两种便宜的、可重复使用的细胞学针型号。在诊断应用中,39例中央型肿瘤中有34例(87%)TBNA结果为阳性,45例周围型结节或肿块中有31例(69%)TBNA结果为阳性。在19例患者中,TBNA是唯一的阳性样本。在分期应用中,90例肿瘤扩散压迫气道壁的病例中有41例(46%)TBNA结果为阳性。当穿刺部位的气管或支气管在内镜下正常时,20例病例中只有3例(15%)TBNA结果为阳性。这些结果表明,TBNA作为一种诊断工具是有效的。然而,它在分期方面似乎效果较差,在分期中,要通过TBNA获得良好的阳性率可能需要CT阳性结果并使用组织学针。