Ishikawa K, Higa I, Suzuki K, Horiba M
Department of Urology, Hiratsuka Municipal Hospital, Japan.
Hinyokika Kiyo. 1996 Mar;42(3):187-9.
A clinical study was performed in 13 cases of refractory Enterococcus faecalis pyelonephritis that were detected in the Department of Urology, Hiratsuka Municipal Hospital, from April 1975 to March 1995. The characteristic features were that pyelonephritis was commonly seen in females, and clinical symptoms (low-grade intermittent fever, low back pain, general malaise, etc.) were continuously refractory. Bacteriuria or polymicrobial infections were often found, and bacterial count was often as high as 10(2)-10(4)/ml. Nevertheless we considered that E. faecalis caused of refractory pyelonephritis must not have week adherence and pathogenesis to the kidney, owing to the clinical symptoms and the basic subjects. Furthermore this infection was difficult to cure completely with antimicrobials having activity against E. faecalis, and long-term treatment was needed. Therefore, we recommend that treatment for refractory E. faecalis pyelonephritis be carefully selected according to clinical symptoms and the bacterial density of this strain.
1975年4月至1995年3月期间,在平冢市立医院泌尿外科检测出13例难治性粪肠球菌肾盂肾炎,并进行了一项临床研究。其特征为肾盂肾炎常见于女性,临床症状(低热间歇性发热、腰痛、全身不适等)持续难治。经常发现菌尿或混合感染,细菌计数通常高达10(2)-10(4)/ml。然而,考虑到临床症状和基础情况,我们认为导致难治性肾盂肾炎的粪肠球菌对肾脏的黏附力和致病机制一定不强。此外,这种感染很难用对粪肠球菌有活性的抗菌药物完全治愈,需要长期治疗。因此,我们建议根据临床症状和该菌株的细菌密度,仔细选择难治性粪肠球菌肾盂肾炎的治疗方法。