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[暴露于多环芳烃慢性免疫抑制人群中的特应性症状]

[Symptoms of atopy in persons exposed to chronic immunosuppression of polycyclic aromatic hydrocarbons].

作者信息

Szczeklik J, Kowalczyk E, Gałuszka Z

机构信息

Kliniki Chorób Wewnetrznych i Zawodowych, Collegium Medicum UJ w Krakowie.

出版信息

Pneumonol Alergol Pol. 1995;63(9-10):502-6.

PMID:8620170
Abstract

The frequency of the atopy symptoms was estimated in 126 coke oven workers chronically exposed to polycyclic aromatic hydrocarbons (PAHs). The assessment was based on questionnaire, point skin tests with the allergens of dust, feathers, mould grass as well as on the measurements of total blood serum IgE concentration. The control group was consisted of 75 men, workers of cold rolling mill division where the environmental conditions were much better. It was observed that positive questionnaire data and positive skin tests were significantly less frequent in men exposed to PAHs. The men serum IgE values were not statistically different in both group workers although in coke oven workers the tendency to higher IgE values was observed. It is rather suggested that more useful method might be the measurement of specific serum IgE.

摘要

对126名长期接触多环芳烃(PAHs)的焦炉工人的特应性症状频率进行了评估。评估基于问卷调查、针对灰尘、羽毛、霉菌等过敏原的点刺皮肤试验以及血清总IgE浓度的测量。对照组由75名男性组成,他们是冷轧厂部门的工人,那里的环境条件要好得多。观察到接触PAHs的男性中,问卷数据阳性和皮肤试验阳性的频率明显较低。两组工人的血清IgE值在统计学上没有差异,尽管在焦炉工人中观察到有IgE值升高的趋势。相当建议更有用的方法可能是测量特异性血清IgE。

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