Wiener K
Clin Chim Acta. 1977 Apr 15;76(2):243-50. doi: 10.1016/0009-8981(77)90103-6.
22 patients suffering from acute myocardial infarction were subjected to daily blood sampling for up to 6 days after admission to hospital. 5 patients with myocardial ischaemia and chest pain, but no evidence of infarction, were similarly investigated as controls. Daily measurements of plasma cortisol, corticosterone, cardiac enzymes and urea were performed. Plasma cortisol was elevated in all except one of the infarction cases and corticosterone was raised in 13 cases. Control patients had normal levels. Infarction patients were divided into three clinical groups: uncomplicated cases, complicated and fatalities. The latter group exhibited the highest levels of cortisol and corticosterone; no significant difference was seen between the other two groups. Uraemia tended to be associated with the complicated cases, particularly the fatalities, but not with uncomplicated cases. The three groups could be differentiated statistically on the basis of plasma urea concentration.
22例急性心肌梗死患者在入院后每天进行血样采集，持续6天。5例有心肌缺血和胸痛但无梗死证据的患者作为对照进行同样的研究。每天测定血浆皮质醇、皮质酮、心肌酶和尿素。除1例梗死病例外，所有梗死病例的血浆皮质醇均升高，13例皮质酮升高。对照患者水平正常。梗死患者分为三个临床组：非并发症病例、并发症病例和死亡病例。后者组皮质醇和皮质酮水平最高；其他两组之间未见显著差异。尿毒症往往与并发症病例特别是死亡病例相关，但与非并发症病例无关。根据血浆尿素浓度，这三组在统计学上可以区分。
