Moss A J, Bissada N K, Boyd C M, Hunter W C
Urology. 1979 Feb;13(2):182-4. doi: 10.1016/0090-4295(79)90292-9.
The role of plasma N-acetyl neuraminic acid (NANA) level in detection and staging prostatic and bladder carcinomas was evaluated. Multiple determinations were obtained in 73 male subjects, including normal controls, patients with prostatic or bladder carcinoma or with benign prostatic hyperplasia. Patients with prostatic or bladder carcinoma had significantly higher NANA levels than normal individuals. Further, in patients with prostatic carcinoma, NANA values correlated well with both the stage of the disease and the response to therapy.
评估了血浆N-乙酰神经氨酸（NANA）水平在前列腺癌和膀胱癌检测及分期中的作用。对73名男性受试者进行了多次测定，包括正常对照组、前列腺癌或膀胱癌患者以及良性前列腺增生患者。前列腺癌或膀胱癌患者的NANA水平显著高于正常个体。此外，在前列腺癌患者中，NANA值与疾病分期及治疗反应均密切相关。
