Middleton M L
Division of Nuclear Radiology, Scott & White Clinic and Memorial Hospital, Temple, TX 76508, USA.
Semin Nucl Med. 1996 Jan;26(1):4-15. doi: 10.1016/s0001-2998(96)80012-2.
Nuclear medicine imaging techniques continue to play a unique role in the evaluation of hepatic masses. Although many useful radiodiagnostic agents are available, the predominant nuclear medicine study used to evaluate hepatic masses in this decade is technetium-labeled red blood cell "blood-pool" scintigraphy. Hepatic blood-pool scintigraphy is extremely useful for the confirmation or exclusion of benign hepatic hemangiomas. This technique was first described in the 1970s and has vastly improved since that time. This improvement has been caused predominantly by advancements in instrumentation, especially the development of single photon emission computed tomography (SPECT) imaging. However, a perfusion/blood-pool mismatch remains unchanged as the hallmark finding for hepatic hemangiomas. The sensitivity and specificity of blood-pool scanning for the detection of hemangiomas has continued to increase over the years, and has not been equaled or surpassed by other radiographic modalities, with the possible exception of magnetic resonance imaging. Furthermore, blood-pool imaging is relatively inexpensive, simple to perform, and highly accurate. When a suspected hepatic hemangioma is confirmed by a positive radionuclide blood-pool study, the clinical evaluation of patients with hepatic masses can generally be terminated.
核医学成像技术在肝脏肿块的评估中继续发挥着独特作用。尽管有许多有用的放射诊断剂，但在这十年中用于评估肝脏肿块的主要核医学检查是锝标记红细胞“血池”闪烁扫描。肝脏血池闪烁扫描对于确认或排除肝脏良性血管瘤极为有用。该技术于20世纪70年代首次被描述，自那时以来有了很大改进。这种改进主要是由仪器的进步引起的，特别是单光子发射计算机断层扫描（SPECT）成像的发展。然而，灌注/血池不匹配仍然是肝脏血管瘤的标志性表现。多年来，血池扫描检测血管瘤的敏感性和特异性持续提高，除了磁共振成像可能是个例外，其他影像学检查方法都无法与之媲美或超越。此外，血池成像相对便宜、操作简单且高度准确。当放射性核素血池检查结果呈阳性从而确诊为疑似肝脏血管瘤时，对肝脏肿块患者的临床评估通常可以终止。
