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腹部脓肿检测:镓、铟-111和锝-99m标记的白细胞以及多克隆和单克隆抗体。

Abdominal abscess detection: gallium, 111In-, and 99mTc-labeled leukocytes, and polyclonal and monoclonal antibodies.

作者信息

Datz F L

机构信息

Department of Radiology, University of Utah School of Medicine, Salt Lake City 84132, USA.

出版信息

Semin Nucl Med. 1996 Jan;26(1):51-64. doi: 10.1016/s0001-2998(96)80016-x.

DOI:10.1016/s0001-2998(96)80016-x
PMID:8623052
Abstract

Computed tomography (CT) and magnetic resonance imaging (MRI) are excellent modalities for imaging patients with localizing signs of an intra-abdominal abscess. However, radionuclide techniques have an advantage over CT and MRI because they can evaluate the entire body for infection. In addition, radionuclides can noninvasively differentiate infection and inflammation from benign fluid collections. Radiopharmaceuticals available for imaging abdominal infection include gallium-67 citrate, indium-111, and technetium-99m-labeled leukocytes, and radiolabeled whole antibodies. The use of these radiopharmaceuticals for abdominal imaging is dependent on their biodistribution and mechanism of abscess localization.

摘要

计算机断层扫描(CT)和磁共振成像(MRI)是对有腹腔内脓肿定位体征的患者进行成像的极佳方式。然而,放射性核素技术相对于CT和MRI具有优势,因为它们可以评估全身是否存在感染。此外,放射性核素能够非侵入性地将感染和炎症与良性液体积聚区分开来。可用于腹部感染成像的放射性药物包括枸橼酸镓-67、铟-111以及锝-99m标记的白细胞,还有放射性标记的全抗体。这些放射性药物用于腹部成像取决于它们的生物分布和脓肿定位机制。

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1
Abdominal abscess detection: gallium, 111In-, and 99mTc-labeled leukocytes, and polyclonal and monoclonal antibodies.腹部脓肿检测:镓、铟-111和锝-99m标记的白细胞以及多克隆和单克隆抗体。
Semin Nucl Med. 1996 Jan;26(1):51-64. doi: 10.1016/s0001-2998(96)80016-x.
2
[Human aspecific gamma globulin labeled with Indium 111: a new radiopharmaceutic agents for the localization of inflammation and infection foci].[用铟111标记的人特异性γ球蛋白:一种用于炎症和感染灶定位的新型放射性药物制剂]
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Imaging of abdominal inflammation using other radioisotope techniques.使用其他放射性同位素技术对腹部炎症进行成像。
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Comparison of 99m technetium hexamethylpropylene-amine oxime labelled leucocyte with 111-indium tropolonate labelled granulocyte scanning and ultrasound in the diagnosis of intra-abdominal abscess.锝-99m六甲基丙烯胺肟标记白细胞与铟-111托品酸酯标记粒细胞扫描及超声检查在腹腔脓肿诊断中的比较
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Indium-111-labeled human nonspecific immunoglobulin G: a new radiopharmaceutical for imaging infectious and inflammatory foci.铟 - 111标记的人非特异性免疫球蛋白G:一种用于感染性和炎症病灶成像的新型放射性药物。
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Imaging experimental intraabdominal abscesses with 99mTc-PEG liposomes and 99mTc-HYNIC IgG.用99mTc-聚乙二醇脂质体和99mTc- HYNI IgG对实验性腹腔内脓肿进行成像。
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The utility of [99mTc]HMPAO-leukocytes for imaging infection.[99mTc]HMPAO标记白细胞在感染成像中的应用。
Semin Nucl Med. 1994 Apr;24(2):110-27. doi: 10.1016/s0001-2998(05)80226-0.

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Imaging experimental intraabdominal abscesses with 99mTc-PEG liposomes and 99mTc-HYNIC IgG.用99mTc-聚乙二醇脂质体和99mTc- HYNI IgG对实验性腹腔内脓肿进行成像。
Ann Surg. 1999 Apr;229(4):551-7. doi: 10.1097/00000658-199904000-00015.