乙酰胆碱诱导特发性长QT综合征患者QT间期延长
Acetylcholine-induced prolongation of the QT interval in idiopathic long QT syndrome.
作者信息
Aizawa Y, Washizuka T, Igarashi Y, Kitazawa H, Chinushi M, Abe A, Shibata A
机构信息
The First Department of Internal Medicine, Niigata University School of Medicine, Asahimachi, Japan.
出版信息
Am J Cardiol. 1996 Apr 15;77(10):879-82. doi: 10.1016/s0002-9149(97)89189-8.
PMID:8623747
Abstract
Intracoronary acetylcholine prolonged the QT interval in 5 patients with congenital long QT syndrome but not in subjects with normal QT intervals. Prolongation was not due to bradycardia or adrenergic drive, and atropine was suggested to attenuate the response.
摘要
冠状动脉内注射乙酰胆碱可使5例先天性长QT综合征患者的QT间期延长，但对QT间期正常的受试者无此作用。QT间期延长并非由心动过缓或肾上腺素能驱动所致，提示阿托品可减弱该反应。
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