Page E, Perrault H, Flore P, Rossignol A M, Pironneau S, Rocca C, Aguilaniu B
Laboratorie de Physiopathologie de l'Exercise, Grenoble, France.
Am J Cardiol. 1996 Apr 15;77(10):892-5. doi: 10.1016/S0002-9149(97)89193-X.
Results from this study showed that patients who underwent successful operation for transposition of the great arteries had no appropriate increase in stroke volume in response to exercise of a nature similar to common recreational activities. The impairment, most likely due to disturbances in both venous return and ventricular systolic function, is compensated for by an increase in peripheral oxygen extraction; however, this increase may not be adequate with maturation or during prolonged exercise when cardiovascular constraints are more important.
这项研究的结果表明，接受大动脉转位成功手术的患者，在进行类似于普通娱乐活动的运动时，心搏量没有相应增加。这种损害很可能是由于静脉回流和心室收缩功能紊乱所致，通过外周氧摄取增加来代偿；然而，随着成熟或在长时间运动时（此时心血管限制更为重要），这种增加可能并不足够。
