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甲状腺癌导致的进行性嗜酸性粒细胞增多伴肺结节

Progressive hypereosinophilia with lung nodules due to thyroid carcinoma.

作者信息

Miller W M, Adcook K J, Moniot A L, Raymond L W, Hutcheson J, Elliott R C

出版信息

Chest. 1977 Jun;71(6):789-91. doi: 10.1378/chest.71.6.789.

DOI:10.1378/chest.71.6.789
PMID:862454
Abstract

An elderly woman had dyspnea, a thyroid mass and multiple lung nodules on chest radiographs. She developed hypereosinophilia over a three-month period in which multiple diagnostic procedures were performed, without definition of the disease process. At post-mortem examination, the primary lesion was found to be a poorly differentiated carcinoma of the thyroid, metastatic to lung. This is the second case of hypereosinophilia related to metastatic thyroid carcinoma. The intensity of the hypereosinophilia in this case was increased by the administration of thyroid-stimulating hormone and by the development of necrosis of the lung nodules.

摘要

一位老年女性出现呼吸困难,胸部X线片显示甲状腺有肿物及多个肺结节。在三个月内她出现了嗜酸性粒细胞增多症,在此期间进行了多项诊断性检查,但未明确疾病进程。尸检发现原发性病变是甲状腺低分化癌,已转移至肺部。这是第二例与转移性甲状腺癌相关的嗜酸性粒细胞增多症病例。该病例中嗜酸性粒细胞增多症的程度因促甲状腺激素的使用及肺结节坏死的发生而加重。

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