Breza J
Urologická klinika Lekárskej fakulty Univerzity Komenského, Bratislave.
Bratisl Lek Listy. 1995 Dec;96(12):642-50.
Erectile dysfunction (ED) is the most frequent form of male sexual dysfunctions. The incidence is not known. Approximately 10% of men suffer from ED. Aging is concomitted by an exponential increase in the occurrence of erectile dysfunctions. Some groups of men (suffering from diabetes, alcoholism, ICHS, renal diseases) yield several times higher values of their occurrence. In general, ED (formerly impotentio coeundi) can be defined as an inability to achieve erection and maintain it for an appropriately long period enabling sexual intercourse. ETIOPATHOGENESIS: The etiology includes psychological, neurological, arterial, sinusoidal, venous and hormonal factors which participate in erectile function. ED arises predominantly in consequence of impaired haemodynamics of the penis. It develops either due to insufficient blood inflow into the erectile bodies or due to their excessive drainage. The traumatic lesions of penile vessels are less frequent. Drugs and medicaments play a significant role among etiologic factors causing erectile dysfunctions.
No regulations and principles are generally valid in coincidence with examination of patients with erectile dysfunction. The signs of neurologic, hormonal and vascular defects are detected. An objective method of examination of erectile capacity of the penis resides in the monitoring of penile nocturnal tumescensions. The examination of arterial system of the penis provides information on the perfusion pressure and blood flow in the cavernous arteries. The vascular structures of the penis and their functions can be evaluated by means of duplex ultrasonography and flowmetry. The quality to arterial supply to erectile bodies is evaluated by dynamic examination of arteries prior to and after intracavernous application of vasoactive substances. The functional state and size of venous leak from the cavernous bodies are evaluated by dynamic cavernosometry.
The application of vasoactive substances meant a significant contribution to the diagnosis establishment and therapy of erectile dysfunctions. They have a common feature which resides in their myorelaxation effect and thus in their ability to induce erection by means of relaxation of the smooth muscles of cavernous bodies. Intracavernous application of vasoactive substances is the mostly spread means of therapy of erectile dysfunction as a whole, frequently with no regard to the etiology. Surgical therapy of vasculogenous impotence is based on knowledge concerning the impact of vascular lesions on the haemodynamics of erectile function of the penis. the revascularisation operations are aimed at the regeneration of normal haemodynamic conditions in the penis.
Sexual life is currently considered as a proportion of life of individuals. The physicians therefore have to seek ways of how to help the patients who due to acquired erectile dysfunctions are handicapped in the establishment of family harmony and sexual life. (Ref. 31).
勃起功能障碍(ED)是男性性功能障碍最常见的形式。其发病率尚不清楚。约10%的男性患有ED。随着年龄增长,勃起功能障碍的发生率呈指数级上升。某些男性群体(患有糖尿病、酗酒、先天性高促性腺激素性功能减退症、肾脏疾病)的发生率要高出数倍。一般来说,ED(以前称为性交不能)可定义为无法勃起并维持足够长的时间以进行性交。
病因包括参与勃起功能的心理、神经、动脉、海绵体、静脉和激素因素。ED主要是由于阴茎血流动力学受损所致。它的发生要么是由于进入勃起组织的血液流入不足,要么是由于其过度引流。阴茎血管的创伤性损伤较少见。药物在导致勃起功能障碍的病因中起重要作用。
对于勃起功能障碍患者的检查,一般没有普遍适用的规则和原则。可检测到神经、激素和血管缺陷的体征。一种客观检查阴茎勃起能力的方法是监测阴茎夜间勃起情况。阴茎动脉系统检查可提供海绵体动脉灌注压和血流的信息。阴茎的血管结构及其功能可通过双功超声检查和血流测量来评估。通过在海绵体内应用血管活性物质前后对动脉进行动态检查,评估勃起组织的动脉供血质量。通过动态海绵体测压评估海绵体静脉漏的功能状态和大小。
血管活性物质的应用对勃起功能障碍的诊断和治疗有重大贡献。它们有一个共同特点,即具有肌松弛作用,从而能够通过松弛海绵体平滑肌来诱导勃起。海绵体内应用血管活性物质是治疗勃起功能障碍最常用的方法,通常不考虑病因。血管性阳痿的手术治疗基于对血管病变对阴茎勃起功能血流动力学影响的认识。血管重建手术旨在恢复阴茎正常的血流动力学状态。
性生活目前被视为个人生活的一部分。因此,医生必须寻找方法来帮助那些因后天性勃起功能障碍而在建立家庭和谐和性生活方面受到阻碍的患者。(参考文献31)