Tukei P M
Virus Research Centre, Kenya Medical Research Institute, Nairobi, Kenya.
East Afr Med J. 1996 Jan;73(1):27-31.
Marburg and Ebola viruses are members of the filovirus family that can be regarded as recently emerged. These viruses have caused sporadic outbreaks of fatal haemorrhagic disease in Africa, Europe and recently in the USA. The case fatality rates rank among the highest ranging from 33-80%. The mode of transmission of these viruses are clearly through close contact with blood and body fluids. Disease outbreaks have been amplified in hospital situations with poor blood precautions. In villages disease has been amplified through contamination with blood and fluids during nursing the sick and burial rituals. The source of the viruses has eluded discovery and new theories regarding the nature of these viruses are being entertained. The threat of new outbreaks in Africa is real since serological evidence of the presence of the virus has been documented in Kenya, Sudan, Zaire, Zimbabwe, Gabon, Cote-d'Ivoire and Gabon.
马尔堡病毒和埃博拉病毒是丝状病毒科的成员,可被视为近期出现的病毒。这些病毒在非洲、欧洲以及最近在美国引发了散发性致命出血热疫情。病死率高达33%至80%,位居最高之列。这些病毒的传播途径显然是通过与血液和体液的密切接触。在医院里,由于血液防护措施不力,疫情得以扩大。在村庄中,照顾病人和丧葬仪式期间血液和体液的污染导致了疾病的传播。病毒的源头尚未找到,关于这些病毒本质的新理论也在不断探讨。由于在肯尼亚、苏丹、扎伊尔、津巴布韦、加蓬、科特迪瓦和加蓬都有该病毒存在的血清学证据,非洲再次爆发疫情的威胁是切实存在的。