Lantos P L
Experientia. 1977 Apr 15;33(4):521-2. doi: 10.1007/BF01922250.
The fine structure of early cell proliferations induced transplacentally by ethylnitrosourea in the rat brain reveals that the cells show features of the undifferentiated cells of the subependymal plate: high nuclear-cytoplasmic ratio, scarity of cell organelles and dominance of free over membrane-bound ribosomes. These findings suggest that most, if not all, gliomas induced by ethylnitrosourea originate from these primitive cells.
大鼠脑中经胎盘由乙基亚硝基脲诱导的早期细胞增殖的精细结构显示，这些细胞呈现出室管膜下板未分化细胞的特征：核质比高、细胞器稀少且游离核糖体多于附着核糖体。这些发现表明，由乙基亚硝基脲诱导的大多数（如果不是全部）胶质瘤起源于这些原始细胞。
