构巢曲霉中的分解代谢物阻遏；谷氨酰胺合成酶的作用。
Catabolite repression in Aspergillus nidulans; the role of glutamine synthetase.
作者信息
Bartnik E, Piotrowska M
出版信息
Acta Microbiol Pol. 1978;27(4):303-8.
PMID:86277
Abstract
A mutant (nit8) with a lowered activity of glutamine synthetase (GS) was isolated in Aspergillus nidulans. The levels of GS and of an arginine catabolic enzyme, ornithine transaminase (OTA) were assayed under a variety of growth conditions leading to repression, depression and induction of OTA in the wild type, nit8 and several regulatory mutants. The results obtained appear to exclude the possibility of involvement of GS in the regulation of arginine catabolism in A. nidulans.
摘要
在构巢曲霉中分离出一株谷氨酰胺合成酶（GS）活性降低的突变体（nit8）。在多种生长条件下测定了野生型、nit8和几个调控突变体中GS以及精氨酸分解代谢酶鸟氨酸转氨酶（OTA）的水平，这些条件会导致野生型中OTA的阻遏、去阻遏和诱导。所获得的结果似乎排除了GS参与构巢曲霉精氨酸分解代谢调控的可能性。
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