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小剂量抗利尿激素对急性垂体切除并用生理盐水负荷的大鼠肾脏钠和水排泄的影响。

The effect of small doses of antidiuretic hormone on renal excretion of sodium and water in saline loaded acutely hypophysectomized rats.

作者信息

Ponec J, Lichardus B

出版信息

Experientia. 1977 May 15;33(5):685-6. doi: 10.1007/BF01946576.

DOI:10.1007/BF01946576
PMID:862819
Abstract

Small doses of vasopressin (200 micronU min-1 kg-1) did not influence the loss of ability of acutely hypophysectomized rats to react by natriuresis to the extracellular fluid volume expansion with saline, inspite of restoring their arterial blood pressure to normal. It is concluded that the level of antidiuretic hormone efficient enough to concentrate urine is not a decisive factor in the homeostatic mechanism promoting the 'volume' natriuresis.

摘要

小剂量血管加压素(200微单位·分钟⁻¹·千克⁻¹)尽管能使急性垂体切除大鼠的动脉血压恢复正常,但并未影响其对生理盐水所致细胞外液量增加产生利钠反应的能力丧失。由此得出结论,足以使尿液浓缩的抗利尿激素水平并非促进“容量性”利钠的稳态机制中的决定性因素。

相似文献

1
The effect of small doses of antidiuretic hormone on renal excretion of sodium and water in saline loaded acutely hypophysectomized rats.小剂量抗利尿激素对急性垂体切除并用生理盐水负荷的大鼠肾脏钠和水排泄的影响。
Experientia. 1977 May 15;33(5):685-6. doi: 10.1007/BF01946576.
2
The influence of neurohypophysial hormones on renal function in the acutely hypophysectomized rat.神经垂体激素对急性垂体切除大鼠肾功能的影响。
J Physiol. 1986 Dec;381:439-52. doi: 10.1113/jphysiol.1986.sp016337.
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Decreased free water excretion after indomethacin in the absence of antidiuretic hormone in saline loaded hypophysectomized Wistar and hydrapaenic Brattleboro rats.
Endokrinologie. 1980 Jan;75(1):67-76.
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The influence of beta-adrenoceptive receptor blocking agents on urinary function in the rat.β-肾上腺素能受体阻断剂对大鼠泌尿功能的影响。
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Relations between the cortico-papillary osmotic gradient and saline diuresis in normal and acutely hypophysectomized rats.正常及急性垂体切除大鼠皮质-乳头体渗透梯度与盐水利尿之间的关系
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引用本文的文献

1
The influence of neurohypophysial hormones on renal function in the acutely hypophysectomized rat.神经垂体激素对急性垂体切除大鼠肾功能的影响。
J Physiol. 1986 Dec;381:439-52. doi: 10.1113/jphysiol.1986.sp016337.

本文引用的文献

1
On the role of the hypophysis in the renal mechanism of body fluid volumes regulation.
Endokrinologie. 1973 Jun;61(3):403-12.
2
On the role of antidiuretic hormone in volume natriuresis and polyuria in rats.
Experientia. 1973 Nov 15;29(11):1353. doi: 10.1007/BF01922812.
3
Neurohypophyseal origin of a humoral factor restoring volume natriuresis in acutely hypophysectomized rats.
Experientia. 1972 Dec 15;28(12):1443-4. doi: 10.1007/BF01957839.