The evaluation of clastogenic potential of trichloroacetic acid (TCA) in chick in vivo test system.
作者信息
Bhunya S P, Jena G B
机构信息
Laboratory of Genetic Toxicology and Wildlife Genetics P.G. Department of Zoology, Utkal University, Orissa, India.
出版信息
Mutat Res. 1996 Apr 6;367(4):254-9.
PMID:8628333
Abstract
The objective of the present study was to evaluate the genotoxic potential of trichloroacetic acid (TCA) in chick bone marrow chromosomes, and the experiment was designed to study the dose, route, time and acute vs. sub-acute (fractionated) yield effects of the chemical. TCA induced chromosomal aberrations in a dose, route and time response manner. The results revealed the genotoxic property of TCA in the tested system.
摘要
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