Wolin M J, Trent R G, Lavin P J, Cornblath W T
Anderson Eye and Ear Associates, SC 29622-1226, USA.
Ophthalmology. 1996 Jan;103(1):177-80. doi: 10.1016/s0161-6420(96)30743-4.
The one-and-a-half syndrome is an eye movement disorder characterized by a unilateral gaze palsy and an ipsilateral internuclear ophthalmoplegia. The authors describe a previously unrecognized association between the one-and-a-half syndrome and oculopalatal myoclonus (OPM).
Five clinical cases are presented, with pertinent physical findings and radiologic studies.
A previously unrecognized association of the one-and-a-half syndrome with subsequent development of OPM appears to exist. Involvement of the facial nerve in patients with the one-and-a-half syndrome may be a predictor of the subsequent development of OPM.
Patients with the one-and-a-half syndrome and facial nerve palsy should be followed closely for possible future development of OPM.
一个半综合征是一种眼球运动障碍，其特征为单侧凝视麻痹和同侧核间性眼肌麻痹。作者描述了一种此前未被认识到的一个半综合征与眼腭肌阵挛（OPM）之间的关联。
介绍了5例临床病例，并给出了相关体格检查结果和影像学研究。
一个半综合征与随后发生OPM之间似乎存在一种此前未被认识到的关联。一个半综合征患者的面神经受累可能是随后发生OPM的一个预测指标。
对于患有一个半综合征和面神经麻痹的患者，应密切随访，以观察其未来是否可能发生OPM。
