Talesnik A, Markowitz B, Calcaterra T, Ahn C, Shaw W
Division of Plastic and Reconstructive Surgery, University of California, School of Medicine, Los Angeles, USA.
Plast Reconstr Surg. 1996 May;97(6):1167-78. doi: 10.1097/00006534-199605000-00011.
Thirty-nine patients underwent reconstruction of composite mandibular defects following resection for squamous cell carcinoma. Thirty-four underwent immediate reconstruction, while 5 were reconstructed secondarily. Twenty-one received soft-tissue reconstruction only with a pectoralis major myocutaneous flap, 14 underwent osteocutaneous free-tissue transfer, and 4 received a reconstruction plate with free-tissue transfer for soft-tissue coverage. The mandibular defects in the pectoralis major myocutaneous flap group tended to be posterolateral, while free-tissue transfer defects were more severe, usually involving the anterior mandible. Length of surgery and duration of intensive care unit care were significantly longer for free-tissue transfer patients, while flap complications were more common in the pectoralis major myocutaneous flap patients. Facial appearance scores were higher for the free-tissue transfer group by both patient and physician assessment. Social function, speech, and oral function did not differ significantly. Patients reconstructed secondarily with free-tissue transfer reported significant improvement in appearance, oral continence, and social function, with little change in speech intelligibility, deglutition, or diet tolerance. The cost of the main hospitalization was significantly higher in the free-tissue transfer group than in the pectoralis major myocutaneous flap group, although when the costs of subsequent hospitalizations are included, the difference in total cost narrows. Despite more adverse defects, free-tissue transfer provided more predictable aesthetic results and expeditious return to normal social function than did pectoralis major myocutaneous flap reconstruction. The fiscal impact of these complex reconstructions is, however, significant. Cost-containment issues are presented and recommendations are made.
39例患者因鳞状细胞癌切除后接受了下颌骨复合缺损的重建。34例患者接受了即刻重建,5例患者接受了二期重建。21例患者仅采用胸大肌肌皮瓣进行软组织重建,14例患者接受了骨皮瓣游离组织移植,4例患者接受了带游离组织移植的重建钢板以覆盖软组织。胸大肌肌皮瓣组的下颌骨缺损多位于后外侧,而游离组织移植组的缺损更严重,通常累及下颌骨前部。游离组织移植患者的手术时间和重症监护病房护理时间明显更长,而胸大肌肌皮瓣患者的皮瓣并发症更常见。通过患者和医生评估,游离组织移植组的面部外观评分更高。社会功能、言语和口腔功能无显著差异。接受二期游离组织移植重建的患者在外观、口腔节制和社会功能方面有显著改善,言语清晰度、吞咽或饮食耐受性变化不大。游离组织移植组的主要住院费用明显高于胸大肌肌皮瓣组,不过,若将后续住院费用计算在内,总费用差异会缩小。尽管缺损更严重,但与胸大肌肌皮瓣重建相比,游离组织移植能提供更可预测的美学效果,并能更快恢复正常社会功能。然而,这些复杂重建的财政影响巨大。文中提出了成本控制问题并给出了建议。