柔红霉素和阿霉素新衍生物与DNA的相互作用。
Interaction of new derivatives of daunorubicin and adriamycin with DNA.
作者信息
Arlandini E, Vigevani A, Arcamone F
出版信息
Farmaco Sci. 1977 May;32(5):315-23.
PMID:862886
Abstract
The interaction of a number of new derivatives of the antitumour antibiotics daunorubicin and adriamycin with calf-thymus DNA has been studied by equilibrium dialysis and low-shear viscosimetry. The results are interpreted in terms of structure of the compounds, also by examining molecular stereomodels.
摘要
通过平衡透析和低剪切粘度测定法研究了抗肿瘤抗生素柔红霉素和阿霉素的多种新衍生物与小牛胸腺DNA的相互作用。还通过检查分子立体模型，根据化合物的结构对结果进行了解释。
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