Srison D, Pornpatkul V
Nakhon Nayok Hospital, Thailand.
Southeast Asian J Trop Med Public Health. 1995 Jun;26(2):347-9.
Six hundred and ninety-four cases of shigellosis in Nakhon Nayok Hospital from January 1985 to December 1993 were studied to determine epidemiologic and microbiological features. Forty-five percent of cases were children under the age of 14 years. The majority of cases were in children under the age of four. The organism was found throughout the year, with peak incidence in June and July. The most common type isolated was Shigella flexneri, about 74.43%. Only 0.32% of organisms were Shigella dysenteriae. Shigella isolates showed a high rate of resistance to ampicillin and co-trimoxazole, in 1993 only 16.67% and 22.22% were sensitive respectively to these 2 drugs, but 100% were still sensitive to nalidixic acid. Fewer cases of shigellosis were isolated in recent years possible due to widespread use of quinolones in the treatment of acute infective diarrhea in adults.
对那空那育医院1985年1月至1993年12月期间的694例志贺菌病病例进行了研究，以确定其流行病学和微生物学特征。45%的病例为14岁以下儿童。大多数病例为4岁以下儿童。全年均发现该病原体，6月和7月发病率最高。分离出的最常见类型是福氏志贺菌，约占74.43%。仅0.32%的病原体为痢疾志贺菌。志贺菌分离株对氨苄西林和复方新诺明耐药率较高，1993年这两种药物的敏感率分别仅为16.67%和22.22%，但对萘啶酸仍100%敏感。近年来志贺菌病分离病例较少，可能是由于喹诺酮类药物在成人急性感染性腹泻治疗中的广泛使用。
