具有非典型特征的乳腺纤维腺瘤：一例报告
Breast fibroadenoma with atypical features: a case report.
作者信息
Kordek R, Biernat W, Kubiak R
机构信息
Department of Cancer Pathology, Medical University of Lodź, Poland.
出版信息
Acta Cytol. 1996 Mar-Apr;40(2):335-8. doi: 10.1159/000333764.
BACKGROUND
Although the cytologic features of fibroadenoma are well established, some of the smears from these tumors cause serious diagnostic problems.
CASE
In the cytologic smears from a deeply located breast nodule in a 53-year-old female we found, besides the typical features of fibroadenoma, atypical cells suggesting carcinoma, with intranuclear indentations, nuclear molding, mitotic activity and intracytoplasmic vacuoles. Histologic examination confirmed the diagnosis of fibroadenoma, but marked ductal cell hyperplasia was also revealed.
CONCLUSION
Some disturbing atypical changes may occur in fibroadenoma smears.
背景
尽管纤维腺瘤的细胞学特征已得到充分确立，但这些肿瘤的一些涂片会引发严重的诊断问题。
病例
在一名53岁女性乳房深部结节的细胞学涂片中，我们发现，除了纤维腺瘤的典型特征外，还有提示癌的非典型细胞，伴有核内凹陷、核型、有丝分裂活性和胞质内空泡。组织学检查确诊为纤维腺瘤，但也显示出明显的导管细胞增生。
结论
纤维腺瘤涂片可能会出现一些令人困扰的非典型变化。
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