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酷似恶性胶质瘤的脑囊尾蚴病:一例报告

Cerebral cysticercosis mimicking malignant glioma: a case report.

作者信息

Silver S A, Erozan Y S, Hruban R H

机构信息

Department of Pathology, Johns Hopkins Hospital, Baltimore, Maryland, USA.

出版信息

Acta Cytol. 1996 Mar-Apr;40(2):351-7. doi: 10.1159/000333767.

Abstract

BACKGROUND

Cysticercosis is the most common parasitic infection of the central nervous system in the United States.

CASE

A case of cerebral cysticercosis radiographically and pathologically mimicked a high grade glioma. A symptomatic solitary cerebral hemispheric lesion in a child, unknown at the time to have been born in Korea and adopted by U.S. residents, was initially evaluated by stereotactically guided needle biopsy and diagnosed as having malignant glioma in accord with the radiographic impression. The subsequently excised mass revealed cysticercus with an exuberant granulomatous inflammation and gliosis surrounding a fibrous-walled cyst.

CONCLUSION

In the setting of a solitary parenchymal cyst, the radiographic differential diagnosis of neurocysticercosis often includes a primary neoplasm. However, to our knowledge, this is the first report of cysticercosis's also simulating a brain neoplasm pathologically.

摘要

背景

囊尾蚴病是美国中枢神经系统最常见的寄生虫感染。

病例

一例脑囊尾蚴病在影像学和病理学上酷似高级别胶质瘤。一名儿童出现有症状的孤立性大脑半球病变,当时不知道其出生于韩国,后被美国居民收养,最初通过立体定向引导下的针吸活检进行评估,并根据影像学表现诊断为恶性胶质瘤。随后切除的肿块显示为囊尾蚴,其周围有一个纤维壁囊肿,伴有旺盛的肉芽肿性炎症和胶质增生。

结论

在孤立性实质囊肿的情况下,神经囊尾蚴病的影像学鉴别诊断通常包括原发性肿瘤。然而,据我们所知,这是囊尾蚴病在病理学上也模拟脑肿瘤的首例报告。

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