Varicella vaccine: rationale and indications for use.

The recently released varicella vaccine is effective and cost-effective. Routine immunization with one dose of varicella vaccine is now indicated for all children 12 months to 18 months of age. Catch-up immunization for children 18 months to 12 years of age is indicated if the child does not have a history of chickenpox. For susceptible persons over 12 years of age, two doses given four to eight weeks apart are recommended. Because the varicella vaccine contains live virus, proper evaluation for contraindications is necessary. The varicella vaccine should be administered subcutaneously and is sensitive to heat.