Dunphy C H, Saravia O, Varvares M A
Department of Pathology, St Louis University Health Sciences Center, Missouri 63104, USA.
Arch Pathol Lab Med. 1996 Mar;120(3):285-7.
We report a rare case of mixed cellularity Hodgkin's disease primarily involving Waldeyer's ring, which was confirmed by immunohistochemistry and gene rearrangement studies. Our literature search revealed only 14 cases of this entity; six of these represented lymphocyte-predominant Hodgkin's disease not confirmed by immunohistochemistry and, thus, were possibly not truly Hodgkin's disease. Our case demonstrates the diagnostic difficulties in this rare entity and we recommend appropriate immunoperoxidase staining in atypical lymphoid proliferations involving otolaryngic mucosa-associated lymphoid tissue.
